Motif ID: FOX{I1,J2}.p2

Z-value: 1.491


Transcription factors associated with FOX{I1,J2}.p2:

Gene SymbolEntrez IDGene Name
FOXI1 2299 forkhead box I1
FOXJ2 55810 forkhead box J2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXI1chr5_+_169465478-0.572.6e-02Click!
FOXJ2chr12_+_8076508-0.097.4e-01Click!


Activity profile for motif FOX{I1,J2}.p2.

activity profile for motif FOX{I1,J2}.p2


Sorted Z-values histogram for motif FOX{I1,J2}.p2

Sorted Z-values for motif FOX{I1,J2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{I1,J2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_19818209 8.522 NM_018993
RIN2
Ras and Rab interactor 2
chr9_+_130719034 5.361 LRRC8A
leucine rich repeat containing 8 family, member A
chr5_+_159368690 5.126 TTC1
tetratricopeptide repeat domain 1
chr5_+_159368721 4.366 TTC1
tetratricopeptide repeat domain 1
chr5_+_159368733 4.032 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr1_-_77457664 3.621 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr2_-_133145539 3.564 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr4_+_167013859 3.353 NM_012464
TLL1
tolloid-like 1
chr2_+_201182187 3.237 AOX1
aldehyde oxidase 1
chr17_+_55098280 3.223 CLTC
clathrin, heavy chain (Hc)
chr5_+_147775652 3.041 FBXO38
F-box protein 38
chr12_+_111375382 2.822 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr4_+_86968069 2.725 ARHGAP24
Rho GTPase activating protein 24
chr3_-_130761967 2.649 PLXND1
plexin D1
chr11_+_57547928 2.634 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr4_+_154397975 2.620 TRIM2
tripartite motif containing 2
chr22_-_41366550 2.608 NM_001165877
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr5_+_55182963 2.597 NM_139017
IL31RA
interleukin 31 receptor A
chr2_-_40593074 2.581 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_-_134042500 2.504 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr2_-_215998181 2.383 FN1
fibronectin 1
chr21_+_39117064 2.297 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr13_-_35327798 2.198 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr10_-_90702490 2.183 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr9_+_102380156 2.160 NM_001018116
MURC
muscle-related coiled-coil protein
chr5_+_53787187 2.119 NM_006308
HSPB3
heat shock 27kDa protein 3
chr7_+_111908143 2.114 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr12_-_50871953 2.096 NM_001081492
NM_182507
KRT80

keratin 80

chr15_+_76345577 2.096 NM_001130183
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr9_+_130722994 2.043 NM_001100876
NM_174933
PHYHD1

phytanoyl-CoA dioxygenase domain containing 1

chr2_+_36777406 2.031 VIT
vitrin
chr5_-_54317102 2.030 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr6_-_56615544 2.028 NM_001723
NM_015548
DST

dystonin

chr1_+_148747110 2.011 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr11_-_102250876 1.881 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr8_-_93181091 1.832 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_149611768 1.785 NM_003944
SELENBP1
selenium binding protein 1
chr5_-_59100194 1.755 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr21_+_29439768 1.721 C21orf7
chromosome 21 open reading frame 7
chr9_+_674193 1.716


chr10_+_71231649 1.711 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr12_+_123339662 1.707 NM_181709
FAM101A
family with sequence similarity 101, member A
chr10_+_71231693 1.699 COL13A1
collagen, type XIII, alpha 1
chr10_-_31328426 1.673 NM_001143769
ZNF438
zinc finger protein 438
chr7_-_27186400 1.660 NM_153715
HOXA10
homeobox A10
chr8_-_108579270 1.601 NM_001146
ANGPT1
angiopoietin 1
chr4_+_72321113 1.570 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr3_+_45042754 1.513 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr6_+_74228331 1.507 MTO1
mitochondrial translation optimization 1 homolog (S. cerevisiae)
chr22_+_44828338 1.500


chr2_+_36777336 1.485 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr19_-_56946911 1.436 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr2_-_219906142 1.396 NM_001007089
RESP18
regulated endocrine-specific protein 18 homolog (rat)
chr2_-_179380301 1.387 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr19_-_53187151 1.384 NM_001128326
BSPH1
binder of sperm protein homolog 1
chr5_-_142057692 1.377 NM_001144934
NM_001144935
FGF1

fibroblast growth factor 1 (acidic)

chr1_-_242073094 1.371 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr6_+_153060722 1.359 NM_025107
MYCT1
myc target 1
chr9_+_112470871 1.357 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr2_+_33514896 1.350 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr9_+_132002692 1.346 NM_001128826
NCS1
neuronal calcium sensor 1
chr4_-_68432293 1.345 NM_004262
TMPRSS11D
transmembrane protease, serine 11D
chr11_-_121492010 1.342 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr9_-_8723893 1.332 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr8_-_13416554 1.315 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr16_+_65938753 1.293 NM_001161575
LRRC36
leucine rich repeat containing 36
chr22_-_23500682 1.286 NM_001008496
PIWIL3
piwi-like 3 (Drosophila)
chr8_-_93176618 1.283 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr12_-_14929991 1.278 NM_000900
NM_001190839
MGP

matrix Gla protein

chr3_+_108578877 1.278 NM_032600
CCDC54
coiled-coil domain containing 54
chr4_+_41309482 1.263 LIMCH1
LIM and calponin homology domains 1
chr10_-_14090459 1.260 FRMD4A
FERM domain containing 4A
chr12_+_118100977 1.246 NM_014365
HSPB8
heat shock 22kDa protein 8
chr6_-_152681171 1.243 NM_015293
SYNE1
spectrin repeat containing, nuclear envelope 1
chr9_+_126094067 1.241 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr13_+_20081940 1.224


chr3_-_150569574 1.223 TM4SF1
transmembrane 4 L six family member 1
chr3_-_188936941 1.223 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr3_+_11242666 1.220 NM_001098211
HRH1
histamine receptor H1
chr13_+_96726197 1.206 MBNL2
muscleblind-like 2 (Drosophila)
chrX_+_100361588 1.204 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr3_+_138159396 1.194 NM_144717
IL20RB
interleukin 20 receptor beta
chr19_+_57564981 1.193 NM_001145434
ZNF880
zinc finger protein 880
chr1_-_161439487 1.178 NM_003617
RGS5
regulator of G-protein signaling 5
chr16_+_27248806 1.171 IL4R
interleukin 4 receptor
chr5_-_111340421 1.167 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr1_+_157246305 1.155 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr20_+_19863716 1.142 RIN2
Ras and Rab interactor 2
chr1_-_177106702 1.134 NM_004673
ANGPTL1
angiopoietin-like 1
chr15_+_65205107 1.134 NM_001145102
SMAD3
SMAD family member 3
chr1_-_171286634 1.132 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr7_+_150442652 1.130 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr15_+_37330176 1.121 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr1_+_196148241 1.121 NM_001014434
LHX9
LIM homeobox 9
chr7_-_112513379 1.113 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr2_-_183095308 1.101 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr18_+_53863865 1.097 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr1_+_156229686 1.095 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr13_-_32678142 1.093 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr5_-_119768430 1.091


chr7_+_17349425 1.089 AHR
aryl hydrocarbon receptor
chrX_-_19598912 1.088 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr7_-_27125738 1.087 NM_030661
HOXA3
homeobox A3
chr5_-_36337756 1.081 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr5_+_68702287 1.073 NM_002873
RAD17
RAD17 homolog (S. pombe)
chrX_+_135106578 1.068 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr3_+_46423682 1.067 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr2_-_99412694 1.066 REV1
REV1 homolog (S. cerevisiae)
chr3_+_137224266 1.065 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr1_-_166965034 1.058 NM_001937
DPT
dermatopontin
chr19_+_9157269 1.044 NM_175883
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr2_-_72228427 1.037 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr1_+_22107137 1.035 RPL21
ribosomal protein L21
chr2_+_151922350 1.032 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr18_+_7936885 1.015 PTPRM
protein tyrosine phosphatase, receptor type, M
chr12_-_90100733 1.012 NM_001920
DCN
decorin
chr12_+_26017954 0.996 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr12_-_120220493 0.979 NM_006549
NM_153499
NM_153500
NM_172214
NM_172215
NM_172216
CAMKK2





calcium/calmodulin-dependent protein kinase kinase 2, beta





chr5_+_81636921 0.976 NM_001017971
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr5_-_125956996 0.976 ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr8_-_52884456 0.973 NM_144651
PXDNL
peroxidasin homolog (Drosophila)-like
chr12_-_90100679 0.971 DCN
decorin
chr8_+_32698892 0.961 NM_001159996
NRG1
neuregulin 1
chr13_+_75092570 0.961 NM_005358
LMO7
LIM domain 7
chr9_-_16717887 0.960 BNC2
basonuclin 2
chr6_+_134800533 0.958 LOC154092
hypothetical LOC154092
chr12_+_79362256 0.949 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr11_-_8695974 0.947 ST5
suppression of tumorigenicity 5
chr12_+_47584159 0.946 NM_033124
CCDC65
coiled-coil domain containing 65
chr8_+_120148604 0.941 NM_006438
COLEC10
collectin sub-family member 10 (C-type lectin)
chr16_+_31036474 0.933 NM_032188
NM_182958
MYST1

MYST histone acetyltransferase 1

chr18_-_44723116 0.933 NM_001190823
SMAD7
SMAD family member 7
chr1_-_110735158 0.929 NM_004696
SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr1_+_143807748 0.926 NM_004892
SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chr1_+_84540921 0.920 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr14_+_57964462 0.917 NM_014749
KIAA0586
KIAA0586
chr4_-_186815116 0.911 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr5_+_38439399 0.910 NM_182798
NM_182799
EGFLAM

EGF-like, fibronectin type III and laminin G domains

chr2_-_225519974 0.903 DOCK10
dedicator of cytokinesis 10
chr2_-_215951161 0.901 FN1
fibronectin 1
chr9_-_4290028 0.896 NM_001042413
GLIS3
GLIS family zinc finger 3
chr11_-_128279670 0.894 C11orf45
chromosome 11 open reading frame 45
chr22_+_40372957 0.891 XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr1_-_157950898 0.881 NM_000567
CRP
C-reactive protein, pentraxin-related
chr8_-_93177057 0.879 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr12_-_2814410 0.874 NM_031474
NRIP2
nuclear receptor interacting protein 2
chr1_+_84382529 0.872 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr11_-_101292462 0.869 NM_178127
ANGPTL5
angiopoietin-like 5
chr1_+_66570363 0.861 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr8_+_75066117 0.857 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr19_-_53305825 0.855 NM_001159322
NM_001159323
NM_003706
PLA2G4C


phospholipase A2, group IVC (cytosolic, calcium-independent)


chr19_-_59258846 0.847 NM_198481
VSTM1
V-set and transmembrane domain containing 1
chr13_-_109600709 0.844 COL4A1
collagen, type IV, alpha 1
chr1_+_66570683 0.844 PDE4B
phosphodiesterase 4B, cAMP-specific
chr13_+_22653059 0.840 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr8_-_18710575 0.838 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr6_-_138935359 0.837 NM_020464
NHSL1
NHS-like 1
chr3_+_150675117 0.836 NM_004617
TM4SF4
transmembrane 4 L six family member 4
chr6_+_121798443 0.832 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr2_-_175170674 0.822 WIPF1
WAS/WASL interacting protein family, member 1
chr10_+_94584449 0.819 NM_001013848
EXOC6
exocyst complex component 6
chr2_-_219404755 0.813 NM_017431
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr6_+_151688327 0.812 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr12_-_120219941 0.812 CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr3_+_150675169 0.811 TM4SF4
transmembrane 4 L six family member 4
chr1_-_149245503 0.795 NM_001163259
NM_001163260
NM_001040217
FAM63A


family with sequence similarity 63, member A


chr10_-_116276560 0.795 ABLIM1
actin binding LIM protein 1
chr5_+_149977398 0.790 NM_001166209
SYNPO
synaptopodin
chr2_+_173394560 0.786 NM_001100397
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr11_-_30910074 0.786 NM_020869
DCDC5
doublecortin domain containing 5
chr4_-_186814852 0.785 SORBS2
sorbin and SH3 domain containing 2
chr17_+_53587492 0.784 NM_012374
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chrX_-_43717864 0.783 NM_000266
NDP
Norrie disease (pseudoglioma)
chr8_+_70567581 0.783 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr3_-_170970296 0.782 NM_032487
ARPM1
actin related protein M1
chr21_-_42219849 0.771 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr5_-_59100091 0.768 PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_-_87687276 0.767 SRI
sorcin
chr5_+_159546951 0.764 NM_001130958
FABP6
fatty acid binding protein 6, ileal
chr17_+_7530113 0.761 NM_001143990
WRAP53
WD repeat containing, antisense to TP53
chr1_-_168310232 0.760 NM_014970
KIFAP3
kinesin-associated protein 3
chr9_+_119506274 0.756 NM_138554
TLR4
toll-like receptor 4
chr17_+_33867169 0.753 NM_020876
ARHGAP23
Rho GTPase activating protein 23
chr3_-_102194938 0.751 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr7_+_136203938 0.750 NM_001006627
NM_001006630
CHRM2

cholinergic receptor, muscarinic 2

chr3_-_11598829 0.748 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr9_-_4289915 0.746 GLIS3
GLIS family zinc finger 3
chr16_+_67698943 0.746 NM_005329
HAS3
hyaluronan synthase 3
chr9_-_116608113 0.745 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr18_+_30544193 0.741 NM_001198941
NM_032978
DTNA

dystrobrevin, alpha

chr4_-_54119159 0.741 NM_032622
LNX1
ligand of numb-protein X 1
chr2_+_108571336 0.739 NM_001193488
LIMS1
LIM and senescent cell antigen-like domains 1
chr9_+_5500544 0.739 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr21_-_36774257 0.734 NM_001146079
NM_144492
CLDN14

claudin 14

chr4_-_130233855 0.729 NM_144643
SCLT1
sodium channel and clathrin linker 1
chr14_+_78815406 0.728 NM_001105250
NM_138970
NRXN3

neurexin 3

chr9_-_116920232 0.725 NM_002160
TNC
tenascin C
chr13_-_77391525 0.723


chr4_-_54119123 0.722 LNX1
ligand of numb-protein X 1
chr8_-_93176819 0.720 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.43 6.79e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.41 8.18e-03 GO:0022604 regulation of cell morphogenesis
1.27 2.91e-02 GO:0048519 negative regulation of biological process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.91 2.42e-04 GO:0005578 proteinaceous extracellular matrix
1.72 4.43e-03 GO:0031012 extracellular matrix
1.39 1.34e-02 GO:0044421 extracellular region part

Gene overrepresentation in function category:

enrichment   p-value GO term description
7.17 2.32e-02 GO:0042805 actinin binding